Development of Biomarkers of Healthy Longevity
Longevity
Summary
Supercentenarians, who live to more than 110 years of age, have an extremely long healthspan and are considered to be a model of healthy longevity. At the Center for Supercentenarian Medical Research, we make full use of the bioresources of supercentenarians that has been collected in our medical school over more than 20 years. This research project aims to identify biomarkers of healthy longevity through an integrative Omics technology such as whole genome sequences, single cell transcriptome, gut microbial genes, and iPS cell phenotyping. Furthermore, in collaboration with the ongoing cohort of elderly people with detailed clinical information and imaging data, we will establish "Big Data on Longevity and Cognitive aging" by linking genome/biomarker information and use state-of-the-art AI to create mathematical models for efficient preventive medicine and nursing care systems.
Event Report:
International Centenarian Consortium 2021 online conference (held on June 29, 2021)SDGs
3. GOOD HEALTH AND WELL-BEING
9. INDUSTRY, INNOVATION AND INFRASTRUCTURE
17. PARTNERSHIPS FOR THE GOALSProject Members
About Project Members, ResearchersNote: ◎ indicates the project leader
| Name | Affiliation | Position | Field of Specialization/Research Interests |
|---|---|---|---|
| ◎ Yasumichi Arai | Faculty of Nursing and Medical Care | Professor | Geriatrics and gerontology, Epidemiology of healthy aging and longevity |
| Hideyuki Okano | School of Medicine | Professor | General neuroscience, Nerve chemistry, Nerve pharmacology, Molecular biology, Developmental biology |
| Kohei Itoh(-2021/5/27) | Faculty of Science and Technology | Professor | Condensed matter physics |
| Yasue Mitsukura | Faculty of Science and Technology | Professor | Bio-signal processing, Intelligent informatics, Sensing, denoising, and feature extraction, Sleep engineering |
| Kenya Honda | School of Medicine | Professor | Immunology, Microbiology, Microbiome |
| Takashi Sasaki | School of Medicine | Assistant Professor | Medical Genomics |
| Masaru Mimura | School of Medicine | Professor | Neuropsychology, Geriatric psychiatry |
| Hidehito Niimura | School of Medicine / Graduate School of Human Sciences, Toyo Eiwa Women's University | Assistant Professor / Professor | Neuropsychology, Geriatric psychiatry |
| Ryo Shikimoto | School of Medicine | Project Instructor | Neuropsychology, Geriatric psychiatry |
