Development of Biomarkers of Healthy Longevity

Longevity

Summary

Arai

Supercentenarians, who live to more than 110 years of age, have an extremely long healthspan and are considered to be a model of healthy longevity. At the Center for Supercentenarian Medical Research, we make full use of the bioresources of supercentenarians that has been collected in our medical school over more than 20 years. This research project aims to identify biomarkers of healthy longevity through an integrative Omics technology such as whole genome sequences, single cell transcriptome, gut microbial genes, and iPS cell phenotyping. Furthermore, in collaboration with the ongoing cohort of elderly people with detailed clinical information and imaging data, we will establish "Big Data on Longevity and Cognitive aging" by linking genome/biomarker information and use state-of-the-art AI to create mathematical models for efficient preventive medicine and nursing care systems.

Event Report:

International Centenarian Consortium 2021 online conference (held on June 29, 2021)

SDGs

3. GOOD HEALTH AND WELL-BEING3. GOOD HEALTH AND WELL-BEING
9. INDUSTRY, INNOVATION AND INFRASTRUCTURE9. INDUSTRY, INNOVATION AND INFRASTRUCTURE
17. PARTNERSHIPS FOR THE GOALS17. PARTNERSHIPS FOR THE GOALS

Project Members

About Project Members, Researchers

Note: ◎ indicates the project leader

◎ Yasumichi Arai Faculty of Nursing and Medical Care Professor Geriatrics and gerontology, Epidemiology of healthy aging and longevity
Hideyuki Okano School of Medicine / Graduate School of Medicine Professor / Dean General neuroscience, Nerve chemistry, Nerve pharmacology, Molecular biology, Developmental biology
Kohei Itoh
(-2021/5/27)
Faculty of Science and Technology Professor Condensed matter physics
Yasue Mitsukura Faculty of Science and Technology Professor Bio-signal processing, Intelligent informatics, Sensing and analysis, Soft computing
Kenya Honda School of Medicine Professor Immunology, Microbiology, Microbiome
Takashi Sasaki School of Medicine Assistant Professor Medical Genomics
Masaru Mimura School of Medicine Professor Neuropsychology, Geriatric psychiatry
Hidehito Niimura School of Medicine / Graduate School of Human Sciences, Toyo Eiwa Women's University Assistant Professor / Professor Neuropsychology, Geriatric psychiatry
Ryo Shikimoto School of Medicine Project Instructor Neuropsychology, Geriatric psychiatry