Event/Creativity/Finished

KGRI Lecture Series: (Jan.11, 2018) "Engineering Approaches of Medical Images" *Change of venue

2017.12.27

The Keio University Global Research Institute (KGRI) aims to promote international research and educational exchange and invites those working in the forefront of research and education in Japan and overseas to give lectures.

On this accasion, Dr. Taeyong Lee from Ewha Womans University in Seoul, Korea will give a lecture titled "Engineering Approaches of Medical Images" .


Date and time: Thursday, January 11, 2018  16:45-18:00
*The lecture will begin once preparations are complete after classes have finished.
Venue: 14th Building (Sosokan) 2F Seminar Room 3, Yagami Campus, Keio University
*There has been a change of vanue.
Co-hosts: Department of Mechanical Engineering, Faculty of Science and Technology, Keio University
Keio University Global Research Institute (KGRI)
Language: English (No simultaneous interpretation provided.)
Other: Free admission, Open to anyone, Pre-registration not required

Summary of Lecture:
Osteoporosis is a prevalent problem amongst the elderly. Bone mineral density (BMD) obtained from dual X-ray absorptiometry (DXA) is the golden standard in diagnosing osteopenia (-1.0 < t < -2.5) and osteoporosis (t > -2.5). However, following osteoporosis therapy, increases in BMD may be unreliable. Although hip fracture risk can be reduced with the aid of drugs, treated patients still face considerable risk as most people who sustain hip fracture do not have generalized osteoporosis. A study of the local distribution of bone mass was necessary as they contribute to the geometry and consequently the bone strength. By identifying the respective regions in the femoral neck, the geometric changes were localized and differed between each patient, proving that drug treatment elicits local changes in Rmean and CTmean. Numerical analysis also validated the above findings, where critical strain regions were predicted at similar zones and this is coherent with the fact that reduced thickness of the cortical bone has been related to increased risk of fracture initiation. Hence, from individual radar plots, we can determine if the effect of drugs had outweighed the effect of aging. We can then propose a course of treatment drug better suited for the patient in the clinical scenario. Clinically, little conclusion can be drawn from just the BMD in osteopenic/ osteoporotic patients. This emphasizes the necessity of using geometry and structure to predict fracture risk. Focusing on a patient specific analysis at a local level will improve diagnosis of osteoporosis and ultimately fracture prediction.

Biography:
Taeyong Lee received a Ph.D. degree in Biomedical Engineering from University of Wisconsin-Madison in 2001. He then worked as a post-doctoral fellow in the Orthopaedic Biomechanics Laboratory at Harvard University, followed by a research associate in the department of radiology at Johns Hopkins University. He has served as an Assistant Professor at the National University of Singapore from 2005 till 2014. He is currently an associated professor of Division of Mechanical and Biomedical Engineering at Ewha Womans Univerisyt, Korea. He is a director of the Laboratory for Biomedical Mechanics and Materials at Ewha Womans University.

Poster

Inquiries
Contact persons: Toshihisa Ueda (Professor, Department of Mechanical Engineering, Faculty of Science and Technology)
E-mail: ueda@mech.keio.ac.jp